Small Animal MRI at Ultra-High Fields of 11.7 T

BioSpec 117/16 USR

BioSpec 117/16 USR
BioSpec 117/16 USR

Bruker BioSpin MRI has extended its well-proven BioSpec® series with an 11.7 T Ultra Shielded Refrigerated (USR) system. This is a new milestone in routine MRI because for the first time an actively shielded magnet is available with a horizontal MRI system at this high field strength.
 

Features

  • Ultra high field of 11.7 T with unsurpassed signal-to-noise ratio
  • Ultra shielded refrigerated USR magnets with two-year service intervals
  • Helium zero-boil-off and Nitrogen free magnet technology
  • 72 mm free access for imaging of rats and mice
  • BGA-S integrated gradient and shim systems with the highest slew rates, gradient strengths and outstanding duty cycle performance to overcome high field challenges
  • Scalable Avance™ III architecture for multiple receiver and transmitter channel configuration
  • Phased array coil technology for parallel imaging
  • IntraGate for self-gated cardiac imaging without external triggering devices
  • Motorized and software controlled animal positioning system
  • Routine user interface ParaVision with state-of-the-art MR animal imaging techniques

Technical description

 

The BioSpec 117/16 USR system enables highly resolved routine imaging of the rat brain.
Turbo Spin Echo (RARE) with 68 x 68 µm2 in plane resolution, 0.5 mm slice thickness.

High Resolution Neuroanatomy

The BioSpec 117/16 USR system enables highly resolved  routine imaging of the rat brain leading to outstanding image quality. The signal-to-noise ratio obtained at this field strength allows one to acquire high resolution images of the very tiny in the brain!
 

Diffusion Tensor Imaging
Diffusion Tensor Imaging (DTI) on a rat brain at 11.7T

Diffusion Tensor Imaging

Diffusion Tensor Imaging (DTI) benefits tremendously from the high signal-to-noise ratio that is achieved by the 11.7 T. Images taken in 14 minutes using a EPI-SE sequence: The color coded Eigenvalue image displays the main principle diffusion directions after evaluating 30 different diffusion directions. Diffusion encoding: red: left-right; green: topbottom; blue: in-out.

High resolution fMRI at 11.7 T
High resolution fMRI at 11.7 T

fMRI

High resolution fMRI at 11.7 T demonstrating the excellent BOLD sensitivity at higher magnetic fields (in plane
resolution of 80 x 80 μm2). Courtesy: NIH, Bethesda, MD